NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Reviewed May 26, 2026

Drug-induced nutrient depletion.

Depletion guides·15 nutrients·Reviewed May 2026

Many common medications quietly lower a nutrient over months of use. Each guide lists the medications documented to deplete one nutrient, the mechanism, the biomarker to watch, and what replacement looks like when a prescriber agrees it is warranted.

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Sorted by how many medications are documented to deplete each nutrient.

24 medications · 8 majorCalcium23 medications · 4 majorFolate (Vitamin B9)22 medications · 8 majorMagnesium20 medications · 1 majorVitamin K19 medications · 7 majorSodium18 medicationsZinc16 medicationsCoQ1012 medications · 1 majorVitamin B1212 medications · 4 majorVitamin D12 medications · 3 majorPotassium8 medicationsIron6 medications · 1 majorVitamin B64 medications · 2 majorPhosphorus3 medicationsBiotin (Vitamin B7)3 medicationsVitamin E

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.