Medication·Interactions·Reviewed June 9, 2026
Azathioprine interactions.
Azathioprine has 4 documented interactions in the NutriStack database, including 1 flagged to avoid or as a serious conflict. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Azathioprine at a glance.
A quick, data-grounded summary. The full tables are below.
Azathioprine has 4 documented interactions in the NutriStack database, including 1 flagged to avoid or as a serious conflict. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with azathioprine.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Ashwagandha | Conflict | Ashwagandha may have immune-stimulating effects and could conflict with immunosuppressive treatment goals in autoimmune disease or transplant. |
| Curcumin Phytosome | Caution | Curcumin may have antiplatelet effects and could add to bleeding risk if azathioprine causes thrombocytopenia. |
| Ginkgo Biloba | Caution | Ginkgo may increase bleeding tendency and could compound bleeding risk if azathioprine causes thrombocytopenia. |
| Probiotics | Caution | Live probiotics rarely cause bacteremia or fungemia in severely immunosuppressed patients. |
The full azathioprine profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common azathioprine questions.
Quick answers drawn from the tables above.
What interacts with Azathioprine?
In the NutriStack database, Azathioprine has 4 documented interactions. The most notable include Ashwagandha, Curcumin Phytosome, Ginkgo Biloba, and Probiotics. Check any specific combination before taking it and confirm with your prescriber.
Which substances should I avoid with Azathioprine?
Azathioprine is flagged against 1 substance in the database, including Ashwagandha. These pairings carry a higher risk and should be reviewed with a clinician before combining.
Is it safe to take Ashwagandha with Azathioprine?
NutriStack classifies the Ashwagandha and Azathioprine pairing as conflict: Ashwagandha may have immune-stimulating effects and could conflict with immunosuppressive treatment goals in autoimmune disease or transplant. Avoid without clinician approval when azathioprine is used to prevent rejection or control autoimmune activity. Always confirm with your prescriber.
Check your whole stack
See how azathioprine fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.