Medication·Interactions·Reviewed June 9, 2026
Azelastine interactions.
Azelastine has 3 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Azelastine at a glance.
A quick, data-grounded summary. The full tables are below.
Azelastine has 3 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with azelastine.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Ashwagandha | Caution | Ashwagandha can be sedating in some people and may worsen azelastine-related drowsiness. |
| L-Theanine | Caution | L-theanine may compound fatigue or reduced alertness from azelastine. |
| Melatonin | Caution | Melatonin can add to azelastine-related somnolence and impairment. |
The full azelastine profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common azelastine questions.
Quick answers drawn from the tables above.
What interacts with Azelastine?
In the NutriStack database, Azelastine has 3 documented interactions. The most notable include Ashwagandha, L-Theanine, and Melatonin. Check any specific combination before taking it and confirm with your prescriber.
Is it safe to take Ashwagandha with Azelastine?
NutriStack classifies the Ashwagandha and Azelastine pairing as caution: Ashwagandha can be sedating in some people and may worsen azelastine-related drowsiness. Start one product at a time and avoid use before tasks requiring alertness if drowsy. Always confirm with your prescriber.
Check your whole stack
See how azelastine fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.