Medication·Interactions·Reviewed June 9, 2026
Clopidogrel interactions.
Clopidogrel has 8 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Clopidogrel at a glance.
A quick, data-grounded summary. The full tables are below.
Clopidogrel has 8 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with clopidogrel.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Fish Oil | Caution | Fish oil has antiplatelet properties that may add to clopidogrel's platelet inhibition, increasing the overall bleeding risk. While moderate fish... details → |
| Garlic Extract | Caution | Garlic supplements inhibit platelet aggregation and have been studied head-to-head with clopidogrel. Combined with clopidogrel's irreversible P2Y12... |
| Ginger Extract | Caution | Ginger extract inhibits cyclooxygenase and reduces platelet thromboxane A2 generation. Added to clopidogrel's P2Y12 inhibition, ginger supplements... |
| Ginkgo Biloba | Caution | Ginkgo biloba has significant antiplatelet activity (PAF antagonism) that adds to clopidogrel's platelet inhibition, substantially increasing... details → |
| Nattokinase | Caution | Nattokinase is a fibrinolytic enzyme that degrades fibrin and reduces clotting factors. Combined with clopidogrel's P2Y12-mediated platelet... |
| St. John's Wort | Caution | St. John's Wort induces CYP3A4 and CYP2C19, which are the key enzymes responsible for converting clopidogrel from its inactive prodrug form to its... details → |
| Turmeric/Curcumin | Caution | Curcumin inhibits platelet aggregation through thromboxane A2 synthesis inhibition and GPVI-mediated platelet activation blockade in laboratory... details → |
| Warfarin | Caution | Triple therapy (warfarin + clopidogrel + aspirin) or dual therapy (warfarin + clopidogrel) substantially increases major bleeding risk compared to... details → |
The full clopidogrel profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common clopidogrel questions.
Quick answers drawn from the tables above.
What interacts with Clopidogrel?
In the NutriStack database, Clopidogrel has 8 documented interactions. The most notable include Fish Oil, Garlic Extract, Ginger Extract, Ginkgo Biloba, and Nattokinase. Check any specific combination before taking it and confirm with your prescriber.
Is it safe to take Fish Oil with Clopidogrel?
NutriStack classifies the Fish Oil and Clopidogrel pairing as caution: Fish oil has antiplatelet properties that may add to clopidogrel's platelet inhibition, increasing the overall bleeding risk. While moderate fish oil doses are... Use moderate fish oil doses (1-2g/day) cautiously with clopidogrel. Higher doses may increase bleeding risk. Report any unusual bleeding, bruising,... Always confirm with your prescriber.
Check your whole stack
See how clopidogrel fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.