Medication·Interactions·Reviewed June 9, 2026
Dabigatran interactions.
Dabigatran has 5 documented interactions in the NutriStack database, including 1 flagged to avoid or as a serious conflict. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Dabigatran at a glance.
A quick, data-grounded summary. The full tables are below.
Dabigatran has 5 documented interactions in the NutriStack database, including 1 flagged to avoid or as a serious conflict. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with dabigatran.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| St. John's Wort | Conflict | St. John's wort is a potent P-glycoprotein and CYP3A4 inducer. Because dabigatran etexilate's oral absorption depends on P-gp, induction can... details → |
| Fish Oil | Caution | Fish oil's omega-3 fatty acids reduce platelet thromboxane A2 and can prolong bleeding time. Added to dabigatran's direct thrombin inhibition,... |
| Garlic Extract | Caution | Concentrated garlic supplements inhibit platelet aggregation. Added to dabigatran's direct thrombin inhibition, the antiplatelet effect can raise... |
| Ginkgo Biloba | Caution | Ginkgo biloba inhibits platelet-activating factor and platelet aggregation. Added to dabigatran's direct thrombin inhibition, the antiplatelet... details → |
| Nattokinase | Caution | Nattokinase has fibrinolytic activity and can reduce clotting factors. Dabigatran directly inhibits thrombin, so combining the two may create... |
The full dabigatran profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common dabigatran questions.
Quick answers drawn from the tables above.
What interacts with Dabigatran?
In the NutriStack database, Dabigatran has 5 documented interactions. The most notable include St. John's Wort, Fish Oil, Garlic Extract, Ginkgo Biloba, and Nattokinase. Check any specific combination before taking it and confirm with your prescriber.
Which substances should I avoid with Dabigatran?
Dabigatran is flagged against 1 substance in the database, including St. John's Wort. These pairings carry a higher risk and should be reviewed with a clinician before combining.
Is it safe to take St. John's Wort with Dabigatran?
NutriStack classifies the St. John's Wort and Dabigatran pairing as conflict: St. John's wort is a potent P-glycoprotein and CYP3A4 inducer. Because dabigatran etexilate's oral absorption depends on P-gp, induction can substantially lower... Avoid St. John's wort entirely while taking dabigatran. If you have been taking both, do not stop the dabigatran but stop the St. John's wort and... Always confirm with your prescriber.
Check your whole stack
See how dabigatran fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.