Medication·Interactions·Reviewed June 9, 2026
Empagliflozin interactions.
Empagliflozin has 3 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Empagliflozin at a glance.
A quick, data-grounded summary. The full tables are below.
Empagliflozin has 3 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with empagliflozin.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Alpha-Lipoic Acid | Caution | Alpha-lipoic acid improves insulin sensitivity and lowers fasting glucose, while empagliflozin causes urinary glucose excretion. On empagliflozin... |
| Berberine | Caution | Both empagliflozin and berberine lower blood glucose through different mechanisms. Combined use may increase hypoglycemia risk, particularly when... |
| Chromium | Caution | Empagliflozin lowers blood glucose by causing urinary glucose excretion. Chromium independently improves insulin sensitivity. Used together the... |
The full empagliflozin profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common empagliflozin questions.
Quick answers drawn from the tables above.
What interacts with Empagliflozin?
In the NutriStack database, Empagliflozin has 3 documented interactions. The most notable include Alpha-Lipoic Acid, Berberine, and Chromium. Check any specific combination before taking it and confirm with your prescriber.
Is it safe to take Alpha-Lipoic Acid with Empagliflozin?
NutriStack classifies the Alpha-Lipoic Acid and Empagliflozin pairing as caution: Alpha-lipoic acid improves insulin sensitivity and lowers fasting glucose, while empagliflozin causes urinary glucose excretion. On empagliflozin alone the hypoglycemia... If empagliflozin is your only diabetes medication, ALA can be added with home glucose monitoring for the first 2-4 weeks. If you also take insulin... Always confirm with your prescriber.
Check your whole stack
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