Medication·Interactions·Reviewed June 9, 2026
Evolocumab interactions.
Evolocumab has 4 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Evolocumab at a glance.
A quick, data-grounded summary. The full tables are below.
Evolocumab has 4 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with evolocumab.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Berberine | Caution | Berberine is taken by some patients to lower LDL cholesterol and improve glycemic measures. Mechanistically it is of interest here because berberine... |
| Coenzyme Q10 | Synergy | Coenzyme Q10 (ubiquinone) is sometimes used by patients on lipid-lowering therapy because of concerns about statin-associated muscle symptoms.... |
| Fish Oil | Synergy | Fish Oil may add modest lipid-lowering effects to Evolocumab for triglyceride management. |
| Psyllium Husk | Synergy | Psyllium Husk may add modest lipid-lowering effects to Evolocumab. |
The full evolocumab profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common evolocumab questions.
Quick answers drawn from the tables above.
What interacts with Evolocumab?
In the NutriStack database, Evolocumab has 4 documented interactions. The most notable include Berberine, Coenzyme Q10, Fish Oil, and Psyllium Husk. Check any specific combination before taking it and confirm with your prescriber.
Is it safe to take Berberine with Evolocumab?
NutriStack classifies the Berberine and Evolocumab pairing as caution: Berberine is taken by some patients to lower LDL cholesterol and improve glycemic measures. Mechanistically it is of interest here because berberine upregulates hepatic... If a patient takes berberine, continue lipid monitoring as usual; additive LDL lowering is possible but berberine is not a validated replacement for... Always confirm with your prescriber.
Check your whole stack
See how evolocumab fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.