Medication·Interactions·Reviewed June 9, 2026
Ivabradine interactions.
Ivabradine has 3 documented interactions in the NutriStack database, including 1 flagged to avoid or as a serious conflict. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Ivabradine at a glance.
A quick, data-grounded summary. The full tables are below.
Ivabradine has 3 documented interactions in the NutriStack database, including 1 flagged to avoid or as a serious conflict. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with ivabradine.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| St. John's Wort | Conflict | St. John's Wort can induce CYP3A4 and P-glycoprotein, and systematic reviews identify ivabradine as a drug whose exposure can be reduced by this... details → |
| Magnesium Glycinate | Caution | Ivabradine can cause clinically important bradycardia, and torsades de pointes has been reported when interacting QT-risk drugs are added. Low... |
| Potassium | Caution | Ivabradine lowers heart rate and has rare reports of torsades de pointes when other risk factors are present. Low potassium increases torsades risk... |
The full ivabradine profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common ivabradine questions.
Quick answers drawn from the tables above.
What interacts with Ivabradine?
In the NutriStack database, Ivabradine has 3 documented interactions. The most notable include St. John's Wort, Magnesium Glycinate, and Potassium. Check any specific combination before taking it and confirm with your prescriber.
Which substances should I avoid with Ivabradine?
Ivabradine is flagged against 1 substance in the database, including St. John's Wort. These pairings carry a higher risk and should be reviewed with a clinician before combining.
Is it safe to take St. John's Wort with Ivabradine?
NutriStack classifies the St. John's Wort and Ivabradine pairing as conflict: St. John's Wort can induce CYP3A4 and P-glycoprotein, and systematic reviews identify ivabradine as a drug whose exposure can be reduced by this herb. Lower ivabradine... Avoid St. John's Wort while taking ivabradine unless your prescriber specifically approves and monitors the combination. Do not use dose spacing as... Always confirm with your prescriber.
Check your whole stack
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