Medication·Interactions·Reviewed June 9, 2026
Mesalamine interactions.
Mesalamine has 3 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Mesalamine at a glance.
A quick, data-grounded summary. The full tables are below.
Mesalamine has 3 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with mesalamine.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Probiotics | Synergy | Multi-strain probiotics have been studied as add-ons to 5-ASA therapy, including mesalamine, in ulcerative colitis. Trials of VSL#3-type... details → |
| Saccharomyces Boulardii | Synergy | Saccharomyces boulardii has limited human evidence as an add-on during mesalamine maintenance for mild-to-moderate ulcerative colitis flare... |
| Turmeric/Curcumin | Synergy | Curcumin has randomized-trial and meta-analysis evidence as an adjunct to mesalamine in mild-to-moderate ulcerative colitis. Higher-dose curcumin... details → |
The full mesalamine profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common mesalamine questions.
Quick answers drawn from the tables above.
What interacts with Mesalamine?
In the NutriStack database, Mesalamine has 3 documented interactions. The most notable include Probiotics, Saccharomyces Boulardii, and Turmeric/Curcumin. Check any specific combination before taking it and confirm with your prescriber.
Is it safe to take Probiotics with Mesalamine?
NutriStack classifies the Probiotics and Mesalamine pairing as synergy: Multi-strain probiotics have been studied as add-ons to 5-ASA therapy, including mesalamine, in ulcerative colitis. Trials of VSL#3-type preparations showed improved... Use probiotics as an adjunct, not as a substitute for mesalamine. Choose a product with studied strains and an adequate dose, and reassess symptoms... Always confirm with your prescriber.
Check your whole stack
See how mesalamine fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.