Medication·Interactions·Reviewed June 9, 2026
Prochlorperazine interactions.
Prochlorperazine has 4 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Prochlorperazine at a glance.
A quick, data-grounded summary. The full tables are below.
Prochlorperazine has 4 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with prochlorperazine.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Ginkgo Biloba | Caution | Ginkgo has seizure case reports, and phenothiazines may lower seizure threshold in susceptible patients. |
| Melatonin | Caution | Melatonin can add to prochlorperazine-related sedation, dizziness, and psychomotor impairment. |
| Magnesium Glycinate | Synergy | Low magnesium increases vulnerability to torsades when QT-prolonging drugs are used. |
| Potassium | Synergy | Hypokalemia can increase QT-related arrhythmia risk during prochlorperazine therapy. |
The full prochlorperazine profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common prochlorperazine questions.
Quick answers drawn from the tables above.
What interacts with Prochlorperazine?
In the NutriStack database, Prochlorperazine has 4 documented interactions. The most notable include Ginkgo Biloba, Melatonin, Magnesium Glycinate, and Potassium. Check any specific combination before taking it and confirm with your prescriber.
Is it safe to take Ginkgo Biloba with Prochlorperazine?
NutriStack classifies the Ginkgo Biloba and Prochlorperazine pairing as caution: Ginkgo has seizure case reports, and phenothiazines may lower seizure threshold in susceptible patients. Avoid or use cautiously in seizure disorders or with other seizure-threshold-lowering exposures. Always confirm with your prescriber.
Check your whole stack
See how prochlorperazine fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.