Medication·Interactions·Reviewed June 9, 2026
Raloxifene interactions.
Raloxifene has 4 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Raloxifene at a glance.
A quick, data-grounded summary. The full tables are below.
Raloxifene has 4 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with raloxifene.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Psyllium Husk | Timing Sensitive | Large doses of soluble fiber can reduce or delay absorption of some oral drugs and may make raloxifene exposure less predictable. |
| Calcium | Synergy | Adequate calcium intake supports bone mineralization while raloxifene reduces bone resorption. |
| Vitamin D3 | Synergy | Vitamin D sufficiency improves calcium absorption and supports raloxifene-based osteoporosis care. |
| Vitamin K2 | Synergy | Vitamin K2 is sometimes used for bone matrix protein carboxylation and may overlap with bone-health goals. |
The full raloxifene profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common raloxifene questions.
Quick answers drawn from the tables above.
What interacts with Raloxifene?
In the NutriStack database, Raloxifene has 4 documented interactions. The most notable include Psyllium Husk, Calcium, Vitamin D3, and Vitamin K2. Check any specific combination before taking it and confirm with your prescriber.
Is it safe to take Psyllium Husk with Raloxifene?
NutriStack classifies the Psyllium Husk and Raloxifene pairing as timing sensitive: Large doses of soluble fiber can reduce or delay absorption of some oral drugs and may make raloxifene exposure less predictable. Separate psyllium from raloxifene by at least 2 hours if both are used daily. Always confirm with your prescriber.
Check your whole stack
See how raloxifene fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.