Medication·Interactions·Reviewed June 9, 2026
Terbinafine interactions.
Terbinafine has 3 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Terbinafine at a glance.
A quick, data-grounded summary. The full tables are below.
Terbinafine has 3 documented interactions in the NutriStack database. The full interaction list is below. None of this is a substitute for your prescriber's advice.
Substances that interact with terbinafine.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Alcohol | Caution | Terbinafine is associated with idiosyncratic hepatotoxicity, including cholestatic hepatitis and rare cases of liver failure requiring transplant.... details → |
| NAC | Synergy | Terbinafine is metabolized to a reactive allylic aldehyde (TBF-A) thought to drive its idiosyncratic hepatotoxicity. N-acetylcysteine restores... |
| Probiotics | Synergy | Oral terbinafine treats fungal infections but its mycobiome and microbiome impact in humans is incompletely characterized, and antifungal exposure... |
The full terbinafine profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common terbinafine questions.
Quick answers drawn from the tables above.
What interacts with Terbinafine?
In the NutriStack database, Terbinafine has 3 documented interactions. The most notable include Alcohol, NAC, and Probiotics. Check any specific combination before taking it and confirm with your prescriber.
Is it safe to take Alcohol with Terbinafine?
NutriStack classifies the Alcohol and Terbinafine pairing as caution: Terbinafine is associated with idiosyncratic hepatotoxicity, including cholestatic hepatitis and rare cases of liver failure requiring transplant. Alcohol is a leading... Avoid alcohol throughout the terbinafine course and for at least a few days after it ends. Report any nausea, dark urine, abdominal pain, or... Always confirm with your prescriber.
Check your whole stack
See how terbinafine fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.