Supplement·Interactions·Reviewed June 9, 2026
Artemisinin interactions.
Artemisinin has 5 documented interactions in the NutriStack database: 3 that need timing or caution and 2 that work synergistically. The full list, with what each pairing does, is below.
Artemisinin at a glance.
A quick, data-grounded summary. The full table is below.
Artemisinin has 5 documented interactions in the NutriStack database: 3 that need timing or caution and 2 that work synergistically. The full list, with what each pairing does, is below.
Everything that interacts with artemisinin.
Every supplement and medication in the NutriStack database with a documented interaction with this substance, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| CYP3A4 Substrate Medications | Caution | Artemisinin irreversibly inhibits CYP3A4 (~70%) and CYP2B6. CYP3A4 metabolizes ~50% of all prescription drugs. |
| Iron | Caution | Iron supplementation may modulate artemisinin activity, because artemisinin relies on iron to generate its cytotoxic free radicals and iron status... |
| NAC | Caution | NAC is a potent antioxidant that can quench the reactive oxygen species artemisinin depends on, potentially reducing artemisinin's pro-oxidant effect. |
| Berberine | Synergy | Berberine and artemisinin have shown complementary antiparasitic and antimicrobial activity in some preclinical studies, supporting a tentative... |
| Turmeric/Curcumin | Synergy | Curcumin has been studied as a complementary partner to artemisinin, with preclinical data suggesting added antiparasitic and pro-oxidant effects. |
The full artemisinin profile.
Benefits, dosing by goal, forms, and the cited evidence for this supplement.
Common artemisinin questions.
Quick answers drawn from the table above.
What interacts with Artemisinin?
In the NutriStack database, Artemisinin has 5 documented interactions with other supplements and medications. The most notable include CYP3A4 Substrate Medications, Iron, NAC, Berberine, and Turmeric/Curcumin.
What works well with Artemisinin?
Artemisinin pairs synergistically with Berberine and Turmeric/Curcumin in the NutriStack database. Synergy still depends on dose and timing; open any pair for the detail.
Can you take Artemisinin with CYP3A4 Substrate Medications?
NutriStack classifies the Artemisinin and CYP3A4 Substrate Medications pairing as caution: Artemisinin irreversibly inhibits CYP3A4 (~70%) and CYP2B6. CYP3A4 metabolizes ~50% of all prescription drugs. Review all prescription medications for CYP3A4 metabolism before starting artemisinin.
Check your whole stack
See how artemisinin fits your routine.
NutriStack screens your full stack for interactions and timing conflicts, and updates the moment you change it.