Supplement·Interactions·Reviewed June 9, 2026
Bacopa Monnieri interactions.
Bacopa Monnieri has 9 documented interactions in the NutriStack database: 1 that need timing or caution and 8 that work synergistically. The full list, with what each pairing does, is below.
Bacopa Monnieri at a glance.
A quick, data-grounded summary. The full table is below.
Bacopa Monnieri has 9 documented interactions in the NutriStack database: 1 that need timing or caution and 8 that work synergistically. The full list, with what each pairing does, is below.
Everything that interacts with bacopa monnieri.
Every supplement and medication in the NutriStack database with a documented interaction with this substance, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Alprazolam | Caution | Bacopa Monnieri extract inhibited CYP3A4 in vitro, and alprazolam exposure is clinically increased by CYP3A inhibition. Human data proving a... |
| Alpha-GPC | Synergy | Bacopa monnieri and Alpha-GPC both support cholinergic function through different routes, and are frequently stacked to enhance memory and learning... |
| Ashwagandha | Synergy | Bacopa monnieri and Ashwagandha are traditionally combined in Ayurvedic practice for cognition and stress, with Bacopa supporting memory and... |
| Citicoline | Synergy | The pair supports cholinergic function from two directions, with Citicoline supplying precursor for acetylcholine and membrane phospholipids and... |
| Ginkgo Biloba | Synergy | Ginkgo and bacopa support cognition through complementary routes, and combining them may produce additive memory and processing-speed benefits. |
| L-Theanine | Synergy | Bacopa monnieri and L-theanine are commonly combined for cognitive support, with Bacopa supporting memory consolidation and L-theanine promoting... |
| Lion's Mane | Synergy | The pair supports neuroplasticity by different means, with Lion's Mane stimulating neurotrophic factor production and Bacopa enhancing synaptic... |
| Phosphatidylserine | Synergy | Phosphatidylserine supports neuronal membrane integrity and stress-axis modulation while Bacopa Monnieri enhances cholinergic signaling and synaptic... |
| Rhodiola Rosea | Synergy | Both are adaptogenic and cognition-supporting herbs, and combining them may give additive benefits for stress resilience and mental performance. |
The full bacopa monnieri profile.
Benefits, dosing by goal, forms, and the cited evidence for this supplement.
Common bacopa monnieri questions.
Quick answers drawn from the table above.
What interacts with Bacopa Monnieri?
In the NutriStack database, Bacopa Monnieri has 9 documented interactions with other supplements and medications. The most notable include Alprazolam, Alpha-GPC, Ashwagandha, Citicoline, and Ginkgo Biloba.
What works well with Bacopa Monnieri?
Bacopa Monnieri pairs synergistically with Alpha-GPC, Ashwagandha, Citicoline, Ginkgo Biloba, and L-Theanine in the NutriStack database. Synergy still depends on dose and timing; open any pair for the detail.
Can you take Bacopa Monnieri with Alprazolam?
NutriStack classifies the Bacopa Monnieri and Alprazolam pairing as caution: Bacopa Monnieri extract inhibited CYP3A4 in vitro, and alprazolam exposure is clinically increased by CYP3A inhibition. Human data proving a Bacopa-alprazolam... Use extra caution when starting Bacopa Monnieri if you take alprazolam. Avoid alcohol and other sedatives, and watch for stronger or longer...
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