Supplement·Interactions·Reviewed June 9, 2026
Boron interactions.
Boron has 7 documented interactions in the NutriStack database: 2 that need timing or caution and 5 that work synergistically. The full list, with what each pairing does, is below.
Boron at a glance.
A quick, data-grounded summary. The full table is below.
Boron has 7 documented interactions in the NutriStack database: 2 that need timing or caution and 5 that work synergistically. The full list, with what each pairing does, is below.
Everything that interacts with boron.
Every supplement and medication in the NutriStack database with a documented interaction with this substance, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| DHEA | Caution | Both boron and DHEA can independently raise circulating androgen and estrogen levels. Boron tends to increase free testosterone and estradiol (in... |
| Testosterone | Caution | In a small trial, daily boron 10 mg raised free testosterone and modestly lowered estradiol in healthy men over one week. The clinical impact on top... |
| Calcium | Synergy | Boron reduces urinary calcium excretion and supports calcium utilization for bone health. |
| Magnesium Glycinate | Synergy | Boron has been shown to reduce urinary magnesium loss and raise serum magnesium, supporting magnesium status when the two are taken together. |
| Silicon | Synergy | Both silicon and boron are ultratrace elements repeatedly linked to bone and connective tissue integrity, and they are commonly co-formulated for... |
| Tribulus Terrestris | Synergy | Boron can raise free testosterone by lowering sex hormone binding globulin and reducing conversion of testosterone to estradiol, a mechanism that... |
| Vitamin D3 | Synergy | Boron supports vitamin D metabolism and may increase the half-life of 25(OH)D in the body. |
The full boron profile.
Benefits, dosing by goal, forms, and the cited evidence for this supplement.
Common boron questions.
Quick answers drawn from the table above.
What interacts with Boron?
In the NutriStack database, Boron has 7 documented interactions with other supplements and medications. The most notable include DHEA, Testosterone, Calcium, Magnesium Glycinate, and Silicon.
What works well with Boron?
Boron pairs synergistically with Calcium, Magnesium Glycinate, Silicon, Tribulus Terrestris, and Vitamin D3 in the NutriStack database. Synergy still depends on dose and timing; open any pair for the detail.
Can you take Boron with DHEA?
NutriStack classifies the Boron and DHEA pairing as caution: Both boron and DHEA can independently raise circulating androgen and estrogen levels. Boron tends to increase free testosterone and estradiol (in part by lowering... If stacking, start DHEA at the lowest effective dose (commonly 10 to 25 mg/day) rather than higher doses, and keep boron in the typical supplemental...
Check your whole stack
See how boron fits your routine.
NutriStack screens your full stack for interactions and timing conflicts, and updates the moment you change it.