Supplement·Interactions·Reviewed June 9, 2026
Krill Oil interactions.
Krill Oil has 11 documented interactions in the NutriStack database: 4 that need timing or caution and 7 that work synergistically. The full list, with what each pairing does, is below.
Krill Oil at a glance.
A quick, data-grounded summary. The full table is below.
Krill Oil has 11 documented interactions in the NutriStack database: 4 that need timing or caution and 7 that work synergistically. The full list, with what each pairing does, is below.
Everything that interacts with krill oil.
Every supplement and medication in the NutriStack database with a documented interaction with this substance, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Aspirin Low-Dose | Caution | Krill oil provides omega-3 fatty acids that may have mild antiplatelet effects, which can add to low-dose aspirin in higher-risk situations. Usual... details → |
| Turmeric/Curcumin | Caution | Both have blood-thinning properties. High doses of both together may increase bleeding risk. details → |
| Vitamin E | Caution | High-dose krill oil increases vitamin E requirements because PUFAs are susceptible to peroxidation. May deplete vitamin E stores. details → |
| Warfarin | Caution | Krill oil contains the same omega-3 fatty acids (EPA and DHA) as fish oil, which reduce platelet thromboxane A2 and may prolong bleeding time. The... |
| Astaxanthin | Synergy | Krill oil naturally contains astaxanthin, which protects its PUFAs from oxidation. Additional astaxanthin further enhances antioxidant protection. |
| Coenzyme Q10 | Synergy | CoQ10 is fat-soluble and absorption increases 3-fold when taken with dietary fat. Fish oil provides the ideal fat vehicle. |
| Omega-7 | Synergy | Krill oil supplies omega-3s in phospholipid form plus astaxanthin, complementing omega-7 palmitoleic acid for lipid and metabolic support; many... |
| Phosphatidylserine | Synergy | Phosphatidylserine is a phospholipid that benefits from omega-3 DHA, which is preferentially incorporated into PS in brain membranes. |
| Resveratrol | Synergy | Resveratrol is lipophilic and absorbs better with dietary fat. Both have anti-inflammatory and cardioprotective properties. |
| Vitamin D3 | Synergy | Same synergy as fish oil + D3. Krill oil phospholipid-bound omega-3s provide dietary fat for D3 absorption. details → |
| Vitamin K2 | Synergy | K2 (MK-7) is fat-soluble and absorption increases with dietary fat. Fish oil provides an excellent fat vehicle. details → |
The full krill oil profile.
Benefits, dosing by goal, forms, and the cited evidence for this supplement.
Common krill oil questions.
Quick answers drawn from the table above.
What interacts with Krill Oil?
In the NutriStack database, Krill Oil has 11 documented interactions with other supplements and medications. The most notable include Aspirin Low-Dose, Turmeric/Curcumin, Vitamin E, Warfarin, and Astaxanthin.
What works well with Krill Oil?
Krill Oil pairs synergistically with Astaxanthin, Coenzyme Q10, Omega-7, Phosphatidylserine, and Resveratrol in the NutriStack database. Synergy still depends on dose and timing; open any pair for the detail.
Can you take Krill Oil with Aspirin Low-Dose?
NutriStack classifies the Krill Oil and Aspirin Low-Dose pairing as caution: Krill oil provides omega-3 fatty acids that may have mild antiplatelet effects, which can add to low-dose aspirin in higher-risk situations. Usual omega-3 doses... Use caution with high-dose krill oil while taking low-dose aspirin. Tell your clinician before surgery or dental work, and report unusual bruising,...
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