Protocol·Hormonal Balance·Intermediate·Reviewed June 9, 2026
Hormonal Balance Protocol.
Support hormone-related wellness routines with targeted micronutrients and adaptogens; lab abnormalities, fertility concerns, or endocrine symptoms need clinician evaluation.
The hormonal balance protocol in brief.
A quick summary. The full stack, with dose and timing for each supplement, is below.
The Hormonal Balance Protocol is an intermediate stack of 5 supplements aimed at hormonal balance: Ashwagandha, Vitamin D3, Zinc, Magnesium Glycinate, and Boron. 4 are core and the rest are optional add-ons, at roughly $30-50/mo. Each supplement below lists its dose, timing, role, and the evidence behind it.
What is in the hormonal balance protocol.
Dose, timing, role, and evidence tier for each supplement. Core items carry the protocol; optional ones are situational. Open any name for the full profile.
| Supplement | Dose | Timing | Role | Evidence |
|---|---|---|---|---|
| Ashwagandha | 600 mg | Morning | Core | Strong |
| Vitamin D3 | 1,000-4,000 IU | Morning with food | Core | Moderate |
| Zinc | 30 mg | With food | Core | Strong |
| Magnesium Glycinate | 350 mg | Evening | Core | Moderate |
| Boron | 6 mg | Morning | Optional | Emerging |
KSM-66 and related extracts have been studied for selected testosterone, cortisol, and vitality markers, but effects depend on population and baseline status.
Supports vitamin D status, which is associated with some hormone markers; dose to labs rather than assuming testosterone or thyroid effects.
Zinc deficiency can affect reproductive and immune markers; benefits are most plausible when baseline zinc status is low.
Magnesium has been studied for testosterone and sleep-related markers, but effects depend on baseline status and activity level.
Trace mineral studied for vitamin D and steroid-hormone markers in small studies; evidence remains emerging.
How the pieces combine.
The mechanistic rationale for stacking these together rather than taking them in isolation.
- Ashwagandha and zinc are studied for stress, vitality, and reproductive markers, with strongest rationale when baseline status is low
- Vitamin D + Boron pairing is exploratory and should be guided by labs rather than assumed hormonal effects
- Magnesium may support sleep and selected hormone markers, but it should not be framed as reliably raising testosterone
Cost and commitment.
A rough monthly cost and how involved the protocol is to run.
The evidence behind it.
Overview citations for this protocol. Each supplement's own profile carries its full source list.
- Riachy R et al. Various Factors May Modulate the Effect of Exercise on Testosterone Levels in Men. J Funct Morphol Kinesiol. 2020;5(4):81. PubMed
Common questions.
Quick answers drawn from the stack above.
What is in the Hormonal Balance Protocol?
The Hormonal Balance Protocol combines 5 supplements for hormonal balance: Ashwagandha, Vitamin D3, Zinc, Magnesium Glycinate, and Boron. 4 are core; the rest are optional.
How much does the Hormonal Balance Protocol cost?
NutriStack estimates the Hormonal Balance Protocol at about $30-50/mo, depending on the forms and brands you choose and whether you run the optional add-ons.
Is the Hormonal Balance Protocol backed by evidence?
Each supplement in the protocol carries its own evidence tier (2 rated strong here) and links to PubMed-cited sources. NutriStack does not rank or score brands and takes no manufacturer payments; this is an informational reference, not medical advice.
Build it in the app
Run the hormonal balance protocol in NutriStack.
Add the stack to NutriStack to track timing, screen it for interactions, and see a Stack Score that updates as you tune it.