Protocol·Immunity·Beginner·Reviewed June 9, 2026
Immunity Protocol.
Support normal immune-system nutrient status with commonly studied micronutrients and antioxidants.
The immunity protocol in brief.
A quick summary. The full stack, with dose and timing for each supplement, is below.
The Immunity Protocol is a beginner stack of 5 supplements aimed at immunity: Vitamin C, Zinc, Vitamin D3, Quercetin, and Selenium. 3 are core and the rest are optional add-ons, at roughly $20-35/mo. Each supplement below lists its dose, timing, role, and the evidence behind it.
What is in the immunity protocol.
Dose, timing, role, and evidence tier for each supplement. Core items carry the protocol; optional ones are situational. Open any name for the full profile.
| Supplement | Dose | Timing | Role | Evidence |
|---|---|---|---|---|
| Vitamin C | 1000 mg | Morning | Core | Strong |
| Zinc | 30 mg | With food | Core | Strong |
| Vitamin D3 | 1,000-4,000 IU | Morning with food | Core | Strong |
| Quercetin | 500 mg | With food | Optional | Moderate |
| Selenium | 200 mcg | With food | Optional | Moderate |
Supports epithelial barrier defense, enhances phagocyte function, and promotes lymphocyte proliferation
Essential for T-cell maturation and NK cell activity; deficiency impairs both innate and adaptive responses
Supports immune-response markers when vitamin D status is low; stay within routine upper-limit guidance unless clinician-directed.
Flavonoid studied for immune and inflammatory signaling; zinc-ionophore activity is mainly preclinical and should not be treated as proven antiviral benefit
Cofactor for glutathione peroxidases; optimizes T-cell proliferation and antibody production
How the pieces combine.
The mechanistic rationale for stacking these together rather than taking them in isolation.
- Quercetin has preclinical zinc-ionophore data, but human antiviral benefit from the quercetin-zinc combination is not established
- Vitamin C regenerates vitamin E and enhances selenium-dependent glutathione peroxidase activity
- Vitamin D primes innate immune cells while zinc and selenium optimize adaptive immune responses
Cost and commitment.
A rough monthly cost and how involved the protocol is to run.
The evidence behind it.
Overview citations for this protocol. Each supplement's own profile carries its full source list.
- Gombart AF et al. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020;12(1):236. PubMed
Common questions.
Quick answers drawn from the stack above.
What is in the Immunity Protocol?
The Immunity Protocol combines 5 supplements for immunity: Vitamin C, Zinc, Vitamin D3, Quercetin, and Selenium. 3 are core; the rest are optional.
How much does the Immunity Protocol cost?
NutriStack estimates the Immunity Protocol at about $20-35/mo, depending on the forms and brands you choose and whether you run the optional add-ons.
Is the Immunity Protocol backed by evidence?
Each supplement in the protocol carries its own evidence tier (3 rated strong here) and links to PubMed-cited sources. NutriStack does not rank or score brands and takes no manufacturer payments; this is an informational reference, not medical advice.
Build it in the app
Run the immunity protocol in NutriStack.
Add the stack to NutriStack to track timing, screen it for interactions, and see a Stack Score that updates as you tune it.