Supplement × Prescription·contraindicated·Moderate evidence
L-Tryptophan can increase serotonergic tone and is unsafe with Linezolid's monoamine oxidase inhibitory activity.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. L-Tryptophan can increase serotonergic tone and is unsafe with Linezolid's monoamine oxidase inhibitory activity.
Mechanism. Serotonin precursor loading or serotonergic herbal activity can add to impaired monoamine breakdown and increase serotonin syndrome risk.
Recommendation. Avoid L-Tryptophan while taking Linezolid.
Effect on the composite score
If both L-Tryptophan and Linezolid are in the same stack, this pair applies −25 to your Stack Score (per scored contraindication row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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