From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionInsufficient evidence
What is happening. Ashwagandha may affect thyroid and sedation while epitalon is used for endocrine-adjacent claims.
Mechanism. Overlapping endocrine and sleep-related effects.
Recommendation. Avoid in thyroid disease or pregnancy unless clinician-directed.
Stack Score
How it moves the number.
Effect on the composite score
If both Ashwagandha and Epitalon are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Khavinson VK et al. Peptide regulation of aging. Biogerontology. 2010.Needs sourceNo link