From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionEmerging evidence
What is happening. Both are used for anxiety or stress and may cause additive drowsiness or GI effects.
Mechanism. Additive stress-axis and CNS-calming effects.
Recommendation. Add one at a time and avoid high-dose stacking with sedatives or alcohol.
Stack Score
How it moves the number.
Effect on the composite score
If both Ashwagandha and Lavender are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Kasper S et al. Silexan GAD randomized trial. Int J Neuropsychopharmacol. 2014.Needs sourceNo link