From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionInsufficient evidence
What is happening. Ashwagandha has immune and thyroid effects and could complicate autoimmune or immune-modulating protocols.
Mechanism. Overlapping immunomodulatory effects.
Recommendation. Avoid combining in autoimmune disease or immunosuppression unless a clinician approves.
Stack Score
How it moves the number.
Effect on the composite score
If both Ashwagandha and Thymosin Alpha-1 are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1King R et al. Thymosin alpha 1 review. World J Virol. 2020.Needs sourceNo link