Supplement × Prescription·timing-sensitive·Strong evidence
Cholestyramine can reduce absorption of fat-soluble vitamins including vitamin D.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Cholestyramine can reduce absorption of fat-soluble vitamins including vitamin D.
Mechanism. Bile acid binding reduces micelle-mediated absorption of fat-soluble vitamins.
Recommendation. Separate vitamin D from cholestyramine by at least 4 hours and monitor vitamin D status during long-term therapy.
Effect on the composite score
If both Cholestyramine and Vitamin D3 are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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