NutriStack
Digestive Enzymes and Ox Bile, a synergy.
Ox bile emulsifies dietary fat to improve the action of lipase and other digestive enzymes, supporting more complete fat and fat-soluble nutrient digestion, especially after gallbladder removal.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Digestive Enzymes and Ox Bile
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. Ox bile emulsifies dietary fat to improve the action of lipase and other digestive enzymes, supporting more complete fat and fat-soluble nutrient digestion, especially after gallbladder removal.
Mechanism. Bile salts from ox bile emulsify dietary fats into smaller micelles, increasing the surface area on which pancreatic and supplemental lipase can act to hydrolyze triglycerides.
Recommendation. Take both with fat-containing meals. The combination is commonly used together for fat maldigestion; start low and titrate to comfort.
Sources (2)
- Hofmann AF. The continuing importance of bile acids in liver and intestinal disease. Archives of Internal Medicine, 1999
- Carey MC, Small DM. The physical chemistry of cholesterol solubility in bile. Journal of Clinical Investigation, 1978
Stack Score
How this pair moves the number.
Effect on the composite score
If both Digestive Enzymes and Ox Bile are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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