NutriStack
Iron Bisglycinate and L-Tyrosine, a synergy.
Iron Bisglycinate is a cofactor for tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Iron Bisglycinate and L-Tyrosine
- Pair type
- Synergy
- Evidence (highest tier)
- Strong
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Strong evidence
Synergy
What is happening. Iron Bisglycinate is a cofactor for tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis.
Mechanism. Tyrosine hydroxylase contains a non-heme iron bisglycinate center essential for catalytic activity. Iron Bisglycinate deficiency directly reduces dopamine and norepinephrine synthesis rates.
Recommendation. Ensure adequate iron bisglycinate status when using L-tyrosine for cognitive support. Iron Bisglycinate deficiency impairs catecholamine synthesis.
Sources (1)
- Beard JL et al. Iron deficiency alters brain development and functioning. J Nutr. 2003
Stack Score
How this pair moves the number.
Effect on the composite score
If both Iron Bisglycinate and L-Tyrosine are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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