What kind of interaction is it?

Timing-sensitive: the two substances can be taken on the same day but should be separated by a minimum time window.

Is this interaction backed by published research?

Yes. NutriStack lists 2 citation rows for the Iron Bisglycinate + Levofloxacin pair, each linking to PubMed by PMID where available. Full sourcing methodology at https://nutristackapp.com/methodology/interactions.

Interaction databaseSupplement × PrescriptionReviewed May 2026

Iron Bisglycinate and Levofloxacin, timing-sensitive.

Q: Can I take Iron Bisglycinate and Levofloxacin together?

Yes, if you separate them in time. Iron Bisglycinate and Levofloxacin have a documented timing-sensitive interaction. Iron bisglycinate, despite being a chelated and gentler form, still releases iron available for fluoroquinolone chelation in the gut. Co-administration with levofloxacin reduces antibiotic absorption and can cause treatment failure.

Q: How does this affect a NutriStack Stack Score?

-5 to your Stack Score per scored timing-sensitive row.

Iron bisglycinate, despite being a chelated and gentler form, still releases iron available for fluoroquinolone chelation in the gut. Co-administration with levofloxacin reduces antibiotic absorption and can cause treatment failure.

2 primary source citations. Strong evidence. Last verified May 30, 2026.

Open the interaction checker →Read the methodology

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

Sourcing standards·Evidence tiers

From the interaction database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances: Iron Bisglycinate and Levofloxacin
Pair type: Timing Sensitive
Evidence (highest tier): Strong
Source citations: 2 sources
Stack Score effect: −5 to your Stack Score (per scored timing-sensitive row).
Scope: Supplement × Prescription
Last verified: May 30, 2026

Timing Sensitive · Strong evidence

Timing Sensitive

What is happening. Iron bisglycinate, despite being a chelated and gentler form, still releases iron available for fluoroquinolone chelation in the gut. Co-administration with levofloxacin reduces antibiotic absorption and can cause treatment failure.

Mechanism. Iron from bisglycinate chelates the 3-carboxyl and 4-oxo groups on levofloxacin, forming nonabsorbable complexes in the intestinal lumen.

Recommendation. Take levofloxacin at least 2 hours before or 2 hours after iron bisglycinate. Do not take in the same dose.

Minimum separation. 120

Sources (2)

Stack Score

How this pair moves the number.

Effect on the composite score

If both Iron Bisglycinate and Levofloxacin are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

Check your full routine

One pair was the worked example. NutriStack runs every pair in your stack at once.

Drop in your supplements and prescriptions and the public database surfaces every interaction, synergy, timing rule, and contraindication, every one linked to its primary source.

Open the interaction checker →Browse the full research index