Supplement × Supplement·a synergy·Moderate evidence
Folate status complements B-vitamin metabolism but does not replace niacinamide.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Folate status complements B-vitamin metabolism but does not replace niacinamide.
Mechanism. Different B vitamins support nucleotide synthesis and energy metabolism.
Recommendation. Use together when dietary or lab context supports it.
Effect on the composite score
If both Methylfolate and Niacinamide are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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