From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyEmerging evidence
What is happening. This is a common BPH botanical pairing and may provide complementary LUTS support.
Mechanism. Potentially complementary anti-inflammatory, 5-alpha-reductase, and prostate stromal pathways.
Recommendation. Use a single well-labeled formula and track symptom response rather than stacking multiple blends.
Stack Score
How it moves the number.
Effect on the composite score
If both Saw Palmetto and Stinging Nettle Root are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1NCCIH. Benign prostatic hyperplasia and complementary approaches. 2024.Needs sourceNo link