Interaction databaseSupplement × SupplementReviewed May 2026

Strontium and Vitamin K2, a synergy.

Vitamin K2 supports directing calcium into bone and away from arteries, complementing strontium's bone-building action within a bone-health regimen.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

Sourcing standards·Evidence tiers

From the interaction database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances
Strontium and Vitamin K2
Pair type
Synergy
Evidence (highest tier)
Emerging
Source citations
2 sources
Stack Score effect
+2 to your Stack Score (per scored synergy row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Synergy · Emerging evidence

Synergy

What is happening. Vitamin K2 supports directing calcium into bone and away from arteries, complementing strontium's bone-building action within a bone-health regimen.

Mechanism. Vitamin K2 activates osteocalcin (incorporating calcium into bone) and matrix Gla protein (inhibiting vascular calcification), supporting proper mineral handling while strontium stimulates osteoblasts and curbs resorption.

Recommendation. Reasonable to include vitamin K2 alongside strontium for bone support, especially when calcium and vitamin D are also used. They do not compete for absorption.

Sources (2)
  1. Schurgers LJ et al., Vitamin K-dependent carboxylation of matrix Gla-protein, Thrombosis and Haemostasis, 2008
  2. Knapen MHJ et al., Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women, Osteoporosis International, 2013

Stack Score

How this pair moves the number.

Effect on the composite score

If both Strontium and Vitamin K2 are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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