Strontium and Vitamin K2, a synergy.
Vitamin K2 supports directing calcium into bone and away from arteries, complementing strontium's bone-building action within a bone-health regimen.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Strontium and Vitamin K2
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Vitamin K2 supports directing calcium into bone and away from arteries, complementing strontium's bone-building action within a bone-health regimen.
Mechanism. Vitamin K2 activates osteocalcin (incorporating calcium into bone) and matrix Gla protein (inhibiting vascular calcification), supporting proper mineral handling while strontium stimulates osteoblasts and curbs resorption.
Recommendation. Reasonable to include vitamin K2 alongside strontium for bone support, especially when calcium and vitamin D are also used. They do not compete for absorption.
Sources (2)
- Schurgers LJ et al., Vitamin K-dependent carboxylation of matrix Gla-protein, Thrombosis and Haemostasis, 2008
- Knapen MHJ et al., Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women, Osteoporosis International, 2013
Stack Score
How this pair moves the number.
Effect on the composite score
If both Strontium and Vitamin K2 are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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