Supplement × Supplement·a synergy·Emerging evidence

Banaba Leaf (Corosolic Acid) + Berberine

Synergy Emerging evidence

Both may lower glucose and can increase hypoglycemia risk when stacked.

From the database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, and the recommendation.

Pair type
Synergy
Evidence
Emerging
Source citations
1
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyEmerging evidence

What is happening. Both may lower glucose and can increase hypoglycemia risk when stacked.

Mechanism. Additive glucose uptake and AMPK-related effects.

Recommendation. Monitor glucose and avoid high-dose stacking with diabetes medications.

Stack Score

How it moves the number.

Effect on the composite score

If both Banaba Leaf (Corosolic Acid) and Berberine are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1
  • 1Stohs SJ et al. Lagerstroemia speciosa constituents. Phytother Res. 2012.Needs sourceNo link

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