From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionInsufficient evidence
What is happening. Berberine may lower glucose while GHRP-2 can affect glucose and appetite.
Mechanism. Glucose-lowering supplement effects plus GH/ghrelin-axis effects.
Recommendation. Avoid unsupervised stacking; monitor glucose if a clinician is supervising endocrine testing.
Stack Score
How it moves the number.
Effect on the composite score
If both Berberine and GHRP-2 are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Laferrere B et al. GHRP-2 increases food intake. JCEM. 2005.Needs sourceNo link