Supplement × Supplement·a synergy·Moderate evidence
Both can lower LDL-C through intestinal mechanisms when taken with meals.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Both can lower LDL-C through intestinal mechanisms when taken with meals.
Mechanism. Reduced cholesterol absorption from plant sterols plus bile acid and viscosity effects from soluble fiber.
Recommendation. Increase fiber gradually and separate other medications or supplements if absorption concerns arise.
Space the doses apart by at least this window to avoid the conflict.
Effect on the composite score
If both Beta-Sitosterol and Psyllium Husk are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
Check your full routine
Drop your supplements and prescriptions into NutriStack and it runs every pair at once: every interaction, synergy, timing rule, and contraindication, each linked to its primary source.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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