From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionEmerging evidence
What is happening. Both can cause GI upset, and concentrated extracts may add liver-safety uncertainty in susceptible people.
Mechanism. Potential additive GI intolerance and extract-related hepatic stress.
Recommendation. Use lower doses and avoid in liver disease unless clinician-directed.
Stack Score
How it moves the number.
Effect on the composite score
If both Bitter Melon and Green Tea Extract are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Joseph B et al. Momordica charantia review. J Ethnopharmacol. 2013.Needs sourceNo link