What is happening. St. John's Wort can affect mood and drug metabolism, complicating neurologic care.
Mechanism. CNS and CYP induction confounding.
Recommendation. Avoid combining with injectable neuroactive therapies without clinician review.
Supplement × Supplement·a caution·Insufficient evidence
St. John's Wort can affect mood and drug metabolism, complicating neurologic care.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. St. John's Wort can affect mood and drug metabolism, complicating neurologic care.
Mechanism. CNS and CYP induction confounding.
Recommendation. Avoid combining with injectable neuroactive therapies without clinician review.
Effect on the composite score
If both Cerebrolysin and St. John's Wort are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.