NutriStack
Coenzyme Q10 and Shilajit, a synergy.
Shilajit appears to enhance the mitochondrial action of CoQ10, with preclinical data showing greater ATP recovery and cellular energy production than CoQ10 alone.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
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At a glance
- Substances
- Coenzyme Q10 and Shilajit
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Shilajit appears to enhance the mitochondrial action of CoQ10, with preclinical data showing greater ATP recovery and cellular energy production than CoQ10 alone.
Mechanism. CoQ10 acts in the mitochondrial electron transport chain; shilajit's fulvic acid and dibenzo-alpha-pyrones appear to help stabilize the reduced (ubiquinol) form and support its delivery into mitochondria, improving ATP regeneration.
Recommendation. Reasonable to combine for energy and mitochondrial support. Human evidence is preliminary, so treat the synergy as plausible rather than proven and use standard doses of each.
Sources (2)
- Bhattacharyya S et al., Shilajit and CoQ10 combination on cellular bioenergetics (preclinical), as reported in Life Extension Magazine, 2016
- Carrasco-Gallardo C et al., Shilajit: A Natural Phytocomplex with Potential Procognitive Activity, International Journal of Alzheimer's Disease, 2012
Stack Score
How this pair moves the number.
Effect on the composite score
If both Coenzyme Q10 and Shilajit are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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