Supplement × Supplement·a synergy·Emerging evidence
Luteolin and curcumin both suppress NF-kappaB-driven inflammation and microglial activation, providing complementary anti-inflammatory and neuroprotective signaling.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Luteolin and curcumin both suppress NF-kappaB-driven inflammation and microglial activation, providing complementary anti-inflammatory and neuroprotective signaling.
Mechanism. Convergent inhibition of NF-kappaB and pro-inflammatory cytokine cascades.
Recommendation. Co-supplementation is reasonable for an anti-inflammatory stack. Monitor if combined with anticoagulants given curcumin's antiplatelet potential.
Effect on the composite score
If both Curcumin Phytosome and Luteolin are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
Check your full routine
Drop your supplements and prescriptions into NutriStack and it runs every pair at once: every interaction, synergy, timing rule, and contraindication, each linked to its primary source.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
NutriStack