What kind of interaction is it?

Synergy: a documented combination effect that is stronger or more useful than either substance taken alone.

Is this interaction backed by published research?

Yes. NutriStack lists 1 citation row for the Green Tea Extract + Luteolin pair, each linking to PubMed by PMID where available. Full sourcing methodology at https://nutristackapp.com/methodology/interactions.

Supplement × Supplement·a synergy·Emerging evidence

Green Tea Extract + Luteolin

Q: Can I take Green Tea Extract and Luteolin together?

Yes. The combination of Green Tea Extract and Luteolin produces a measurable benefit. Luteolin and green tea catechins (notably EGCG) share antioxidant and anti-inflammatory polyphenol activity and may provide additive support, though both inhibit drug-metabolizing enzymes.

Q: How does this affect a NutriStack Stack Score?

+2 to your Stack Score per scored synergy row.

Synergy Emerging evidence

Luteolin and green tea catechins (notably EGCG) share antioxidant and anti-inflammatory polyphenol activity and may provide additive support, though both inhibit drug-metabolizing enzymes.

Supplement × Supplement

Open the interaction checker → Read the methodology

From the database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, and the recommendation.

Substances

Green Tea Extract and Luteolin

Pair type

Synergy

Evidence

Emerging

Source citations

Scope

Supplement × Supplement

Last verified

June 4, 2026

SynergyEmerging evidence

What is happening. Luteolin and green tea catechins (notably EGCG) share antioxidant and anti-inflammatory polyphenol activity and may provide additive support, though both inhibit drug-metabolizing enzymes.

Mechanism. Both are polyphenols that scavenge reactive oxygen species and modulate NF-kappaB/Nrf2 pathways.

Recommendation. Reasonable to combine at typical supplemental doses. Be mindful of high-dose green tea extract's rare hepatotoxicity risk and shared CYP/UGT inhibition when taking medications.

Stack Score

How it moves the number.

Effect on the composite score

If both Green Tea Extract and Luteolin are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1Lopez-Lazaro M. Distribution and biological activities of the flavonoid luteolin. Mini-Reviews in Medicinal Chemistry. 2009.Needs sourceNo link

Check your full routine

One pair was the worked example.

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Open the interaction checker → Browse the research index