From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionEmerging evidence
What is happening. Both are commonly used for cognition and can increase headache, dizziness, insomnia, or GI side effects when stacked.
Mechanism. Overlapping CNS-active nootropic effects; ginkgo also has antiplatelet considerations.
Recommendation. Start one product at a time and avoid the combination in people with high fall risk or complex neurologic disease.
Stack Score
How it moves the number.
Effect on the composite score
If both Ginkgo Biloba and Huperzine A are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Yang G et al. Huperzine A for Alzheimer disease. PLoS One. 2013.Needs sourceNo link