Supplement × Prescription·a conflict·Emerging evidence

Ginkgo Biloba + Primidone

Conflict Emerging evidence

Ginkgo may lower seizure threshold and is undesirable with anticonvulsant therapy.

From the database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, and the recommendation.

Substances
Pair type
Conflict
Evidence
Emerging
Source citations
1
Scope
Supplement × Prescription
Last verified
June 4, 2026
ConflictEmerging evidence

What is happening. Ginkgo may lower seizure threshold and is undesirable with anticonvulsant therapy.

Mechanism. Potential seizure-threshold lowering opposes antiseizure therapy.

Recommendation. Avoid ginkgo if primidone is used for seizure prevention.

Stack Score

How it moves the number.

Effect on the composite score

If both Ginkgo Biloba and Primidone are in the same stack, this pair applies −10 to your Stack Score (per scored conflict row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1
  • 1Zesiewicz TA et al. Evidence-based guideline update: treatment of essential tremor. Neurology. 2011.Needs sourceNo link

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