Iron and Psyllium Husk, timing-sensitive.
Psyllium soluble fiber forms a viscous gel in the gut that can bind iron and slow its absorption, lowering the effective dose absorbed when taken together.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Iron and Psyllium Husk
- Pair type
- Timing Sensitive
- Evidence (highest tier)
- Moderate
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored timing-sensitive row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Timing Sensitive · Moderate evidence
Timing Sensitive
What is happening. Psyllium soluble fiber forms a viscous gel in the gut that can bind iron and slow its absorption, lowering the effective dose absorbed when taken together.
Mechanism. The viscous mucilaginous gel formed by psyllium physically traps divalent mineral cations and increases gut transit, reducing the contact time and free iron available for duodenal uptake.
Recommendation. Take iron at least 2 hours apart from psyllium. Dose iron with vitamin C on an empty stomach or between fiber doses.
Minimum separation. 2 hours
Sources (2)
- Fernandez-Banares F, Nutritional care of the patient with constipation, Best Practice and Research Clinical Gastroenterology, 2006. Nutritional care of the patient with constipation. Best Pract Res Clin Gastroenterol. 2006. PMID 16782530
- Anderson JW et al, Health benefits of dietary fiber, Nutrition Reviews, 2009
Stack Score
How this pair moves the number.
Effect on the composite score
If both Iron and Psyllium Husk are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
Check your full routine
One pair was the worked example. NutriStack runs every pair in your stack at once.
Drop in your supplements and prescriptions and the public database surfaces every interaction, synergy, timing rule, and contraindication, every one linked to its primary source.