NutriStack
L-Arginine and Maca Root, a synergy.
The pair approaches sexual function from two angles, with Maca acting on libido and sexual desire while L-Arginine supports the nitric oxide pathway involved in blood flow and erectile response.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- L-Arginine and Maca Root
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. The pair approaches sexual function from two angles, with Maca acting on libido and sexual desire while L-Arginine supports the nitric oxide pathway involved in blood flow and erectile response.
Mechanism. Maca improves sexual desire through central, non-hormonal mechanisms without raising testosterone, while L-Arginine is a substrate for nitric oxide synthase, increasing nitric oxide that relaxes vascular smooth muscle and improves genital blood flow.
Recommendation. May be combined for libido and erectile support. Maca is taken daily over weeks; L-Arginine is often dosed at 1.5 to 5g per day. Use caution with antihypertensives or nitrates given L-Arginine vasodilation.
Sources (2)
- Shin BC, et al. Maca (Lepidium meyenii) for improving sexual function: a systematic review. BMC Complementary and Alternative Medicine. 2010
- Stanislavov R, Nikolova V. Treatment of erectile dysfunction with pycnogenol and L-arginine. Journal of Sex and Marital Therapy. 2003
Stack Score
How this pair moves the number.
Effect on the composite score
If both L-Arginine and Maca Root are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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