NutriStack
L-Theanine and Magnesium L-Threonate, a synergy.
L-theanine and magnesium are both studied for relaxation-related markers, but direct combination evidence is limited.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- L-Theanine and Magnesium L-Threonate
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. L-theanine and magnesium are both studied for relaxation-related markers, but direct combination evidence is limited.
Mechanism. L-theanine has alpha-wave and glutamate-signaling research, while magnesium participates in NMDA/GABA-related physiology. Clinical evidence for the specific combination is limited.
Recommendation. If combining L-theanine with magnesium l-threonate, keep total supplemental magnesium within 200-350 mg/day elemental magnesium unless clinician-supervised; do not frame the pair as anxiety treatment.
Sources (2)
- Kimura K et al. L-theanine reduces psychological and physiological stress responses. Biol Psychol. 2007
- Payne ER, Aceves-Martins M, Dubost J et al.. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. Nutrition Reviews. 2025. PMID 40314930
Stack Score
How this pair moves the number.
Effect on the composite score
If both L-Theanine and Magnesium L-Threonate are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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