NutriStack
Levothyroxine and Magnesium Taurate, timing-sensitive.
Magnesium taurate may interfere with levothyroxine absorption when taken together. This is an extrapolation from magnesium-containing products and other polyvalent cations known to reduce thyroid hormone absorption. The risk is most important when the supplement is taken daily near the thyroid dose.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
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At a glance
- Substances
- Levothyroxine and Magnesium Taurate
- Pair type
- Timing Sensitive
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored timing-sensitive row).
- Scope
- Supplement × Prescription
- Last verified
- May 30, 2026
Timing Sensitive · Emerging evidence
Timing Sensitive
What is happening. Magnesium taurate may interfere with levothyroxine absorption when taken together. This is an extrapolation from magnesium-containing products and other polyvalent cations known to reduce thyroid hormone absorption. The risk is most important when the supplement is taken daily near the thyroid dose.
Mechanism. The magnesium component can bind or reduce dissolution of levothyroxine in the intestinal lumen, decreasing bioavailability. Taurate itself is not the suspected interacting component.
Recommendation. Separate magnesium taurate and levothyroxine by at least 4 hours. Keep your levothyroxine routine consistent and monitor TSH after starting or stopping daily magnesium taurate.
Minimum separation. 240
Sources (2)
- Liwanpo L, Hershman JM. Conditions and drugs interfering with thyroxine absorption. Best Pract Res Clin Endocrinol Metab. 2009;23(6):781-792. PMID 19942153
- Skelin M, Lucijanic T, Amidzic Klaric D, Resic A, Bakula M, Liberati-Cizmek AM, Gharib H, Rahelic D. Factors Affecting Gastrointestinal Absorption of Levothyroxine: A Review. Clin Ther. 2017;39(2):378-403. PMID 28153426
Stack Score
How this pair moves the number.
Effect on the composite score
If both Levothyroxine and Magnesium Taurate are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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