NutriStack
Magnesium Citrate and Vitamin B1, a synergy.
Magnesium is required for thiamine (B1) utilization. Magnesium deficiency impairs thiamine-dependent enzyme activity.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Magnesium Citrate and Vitamin B1
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. Magnesium is required for thiamine (B1) utilization. Magnesium deficiency impairs thiamine-dependent enzyme activity.
Mechanism. Magnesium is required for thiamine pyrophosphokinase, which converts thiamine to its active coenzyme form thiamine pyrophosphate (TPP).
Recommendation. Ensure adequate magnesium when supplementing B1 for proper enzymatic function.
Sources (1)
- Lonsdale D. Thiamine and magnesium deficiencies. Med Hypotheses. 2015
Stack Score
How this pair moves the number.
Effect on the composite score
If both Magnesium Citrate and Vitamin B1 are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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