NutriStack
NAC and Vitamin C Liposomal, a synergy.
NAC replenishes intracellular glutathione, while vitamin C provides extracellular antioxidant support. Complementary antioxidant systems.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- NAC and Vitamin C Liposomal
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. NAC replenishes intracellular glutathione, while vitamin C provides extracellular antioxidant support. Complementary antioxidant systems.
Mechanism. NAC provides cysteine for glutathione synthesis (rate-limiting substrate). Vitamin C Liposomal recycles oxidized glutathione (GSSG) back to reduced GSH and provides parallel antioxidant protection.
Recommendation. Take together for comprehensive antioxidant coverage, glutathione (intracellular) + ascorbate (extracellular).
Sources (1)
- Rushworth GF, Megson IL. Existing and potential therapeutic uses for N-acetylcysteine. Pharmacol Ther. 2014
Stack Score
How this pair moves the number.
Effect on the composite score
If both NAC and Vitamin C Liposomal are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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