Supplement × Supplement·a caution·Insufficient evidence
St. John's Wort can alter drug metabolism and has neuropsychiatric effects; noopept interaction data are lacking.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. St. John's Wort can alter drug metabolism and has neuropsychiatric effects; noopept interaction data are lacking.
Mechanism. CYP/P-gp induction and serotonergic/neuropsychiatric effects may unpredictably interact with CNS-active noopept.
Recommendation. Avoid combining, especially with psychiatric medications or mood instability.
Effect on the composite score
If both Noopept and St. John's Wort are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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