From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
SynergyEmerging evidence
What is happening. Low potassium can increase arrhythmia risk when QT interval is prolonged.
Mechanism. Normal potassium reduces susceptibility to delayed repolarization.
Recommendation. Correct hypokalemia medically; avoid unsupervised potassium in kidney disease or with potassium-retaining drugs.
Stack Score
How it moves the number.
Effect on the composite score
If both Paliperidone and Potassium are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Paliperidone extended-release tablets US Prescribing Information. 2025.Needs sourceNo link