Supplement × Prescription·contraindicated·Strong evidence
St. John's Wort is listed among contraindicated products with rasagiline because of serotonin syndrome risk.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. St. John's Wort is listed among contraindicated products with rasagiline because of serotonin syndrome risk.
Mechanism. Serotonergic herb effects can combine with MAO inhibition.
Recommendation. Do not combine St. John's Wort with rasagiline.
Effect on the composite score
If both Rasagiline and St. John's Wort are in the same stack, this pair applies −25 to your Stack Score (per scored contraindication row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
Check your full routine
Drop your supplements and prescriptions into NutriStack and it runs every pair at once: every interaction, synergy, timing rule, and contraindication, each linked to its primary source.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
NutriStack