From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionInsufficient evidence
What is happening. High-dose vitamin E may increase bruising risk around injections or procedures.
Mechanism. Overlapping procedural bleeding and bruising concern.
Recommendation. Use conservative vitamin E doses and disclose all supplements before procedures.
Stack Score
How it moves the number.
Effect on the composite score
If both Thymosin Beta-4 and Vitamin E are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Sosne G et al. Thymosin beta4 ophthalmic dry eye trial. Clin Ophthalmol. 2015.Needs sourceNo link