Atenolol and Taurine, a caution.
Taurine lowers blood pressure modestly and has direct heart-rate-lowering effects. Combined with atenolol, the effects can be additive, producing further reductions in heart rate and blood pressure.
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At a glance
- Pair type
- Caution
- Evidence (highest tier)
- Moderate
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored caution row).
- Scope
- Supplement × Prescription
- Last verified
- May 30, 2026
Caution · Moderate evidence
Caution
What is happening. Taurine lowers blood pressure modestly and has direct heart-rate-lowering effects. Combined with atenolol, the effects can be additive, producing further reductions in heart rate and blood pressure.
Mechanism. Taurine modulates cardiomyocyte calcium handling, blunts sympathetic outflow, and supports endothelial NO production. These effects add to atenolol's beta1 blockade.
Recommendation. Taurine at 1-3 g/day is typically safe with atenolol but check resting heart rate and blood pressure when you start. Reduce the dose if HR drops below 50 bpm or you develop dizziness.
Sources (2)
- Waldron M, Patterson SD, Tallent J, Jeffries O. The Effects of Oral Taurine on Resting Blood Pressure in Humans: a Meta-Analysis. Curr Hypertens Rep. 2018;20(9):81. PMID 30006901
- Tzang CC, Lin WC, Lin LH, et al. Insights into the cardiovascular benefits of taurine: a systematic review and meta-analysis. Nutr J. 2024;23(1):93. PMID 39148075
Stack Score
How this pair moves the number.
Effect on the composite score
If both Atenolol and Taurine are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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